Learning Green Chemistry Principles by Comparing Three Synthetic Routes to a Copper-NHC (NHC = N-heterocyclic carbene) Complex

This resource links to a recent laboratory experiment published in the Journal of Chemical Education by Francis Bru and Catherine S. K. Cazin, highlighting green chemistry principles by comparing three synthetic routes toward a Copper N-heterocyclic carbene complex. It includes the mechanochemical synthesis using a planetary mill and assessments of several green chemistry metrics, including atom economy, environmental factor, mass intensity, reaction mass efficiency, optimum efficiency, and Green Star analysis.