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Mechanochemistry

Sustainable Preparation of World Health Organization (WHO) Essential Medicines by Mechanochemistry

Graphic for the webinar, Sustainable Preparation of World Health Organization (WHO) Essential Medicines by Mechanochemistry
Event Date
-
Event Type
Hosting Organization(s)
Beyond Benign
Additional Host Organizations
IUPAC CHEMRAWN

Event Description

Although significant efforts have been made to reduce the environmental impact of active pharmaceutical ingredient (API) production, the use of organic solvents—responsible for about 75% of the total energy consumption—remains a critical step in many processes. Solvent-free synthesis through mechanochemistry aligns with several of the 12 Principles of Green Chemistry, offering a more environmentally responsible alternative for chemical synthesis. 

 

Join us for a free webinar on December 9th from 11 a.m. to 12 p.m. EST to hear from Dr. Evelina Colacino, Associate Professor at the University of Montpellier, who will discuss the application of mechanochemical methods to the preparation of World Health Organization essential medicines at various scales. Using green chemistry metrics, we evaluate the environmental and economic benefits of mechanochemistry, demonstrating its potential to advance greener and more sustainable pharmaceutical manufacturing. 

 

🌎 This webinar is part of the “Promoting Chemistry Applied to World Needs” series, hosted by Beyond Benign and the IUPAC Committee on Chemical Research Applied to World Needs (CHEMRAWN). If you haven’t yet registered for this series, sign up here

Event Format
Event Address

United States

Intended Audience

Post-Doctoral Researcher

The Katayev group is looking for a highly motivated postdoctoral researcher to join us in the field of synthetic mechanochemistry, focusing on the discovery of novel catalytic radical and ionic C–H functionalization methodologies and their scale-up using advanced mechanochemical techniques.

Internship 6 months: Mechanocatalyzed synthesis of health-related molecules, optimized by Artificial Intelligence

The internship, sponsored by a “Chem-IA” fellowship from the University of Montpellier, will aim at developing innovative catalytic solutions to make an amide bond, present in many molecules of interest, by a mechanochemistry/machine learning approach.

 

The tasks will include (i) carrying organic mechanochemistry experiments in an extruder (ii) developing an algorithm for a Bayesian optimization approach (iii) applying the developed methods to target molecules such as active pharmaceutical ingredients.

Doctoral researcher in solvent-free synthesis of cellulose-based catalysts

Are you interested in research, particularly in the field of organic chemistry and material science, and enthusiastic about exploring unconventional synthetic strategies? We are now seeking a motivated team player, passionate about developing sustainable material synthesis techniques. Our research focuses on the use of mechanochemical and related solid-state synthesis approaches to make materials under solvent-free or low-solvent conditions, aiming to reduce the waste, cost, and hazards of chemical reactions.