Replacement of Less-Preferred Dipolar Aprotic and Ethereal Solvents in Synthetic Organic Chemistry with More Sustainable Alternatives

This review article provides an overview of dipolar aprotic and ethereal solvents and their use in synthetic organic chemistry, as well as recent legislative changes being imposed on their usage, and alternative, safer and more sustainable alternatives to consider as well as case study examples of where less desirable solvents have been successfully replaced with greener options.